{"id":786005,"date":"2021-12-28T02:42:19","date_gmt":"2021-12-27T18:42:19","guid":{"rendered":"https:\/\/news.seehua.com\/?p=786005"},"modified":"2021-12-28T02:43:12","modified_gmt":"2021-12-27T18:43:12","slug":"%e8%be%89%e7%91%9e%e5%86%a0%e7%97%85%e6%96%b0%e8%8d%af%e8%8b%a5%e4%b8%8e%e9%83%a8%e5%88%86%e8%8d%af%e7%89%a9%e5%b9%b6%e7%94%a8-%e4%b8%93%e5%ae%b6%e8%ad%a6%e5%91%8a%e6%81%90%e6%9c%89%e8%87%b4","status":"publish","type":"post","link":"https:\/\/test.seehua.com\/?p=786005","title":{"rendered":"\u8f89\u745e\u51a0\u75c5\u65b0\u836f\u82e5\u4e0e\u90e8\u5206\u836f\u7269\u5e76\u7528 \u4e13\u5bb6\u8b66\u544a\u6050\u6709\u81f4\u547d\u6027\u526f\u4f5c\u7528"},"content":{"rendered":"\n

\u56fd\u5bb6\u5e7f\u64ad\u516c\u53f8(NBC)\u62a5\u5bfc\uff0c\u8f89\u745e\u836f\u5382(Pfizer)\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u53ca\u836f\u7269\u7ba1\u7406\u5c40(FDA)\u6838\u51c6\u7684\u6297\u65b0\u51a0\u75c5\u6bd2\u53e3\u670d\u7528\u836fPaxlovid\u9e21\u5c3e\u9152\u7597\u6cd5\uff0c\u9047\u5230\u5176\u4ed6\u5904\u65b9\u836f\u7269\u65f6\uff0c\u4f8b\u5982\u6297\u8840\u8102\u836f\u7269\u65bd\u5fb7\u4e01(statins)\u3001\u6297\u51dd\u8840\u5242(blood thinners)\u4e0e\u67d0\u4e9b\u6297\u5fe7\u90c1\u5242(antidepressants)\uff0c\u6050\u5c06\u4ea7\u751f\u6709\u81f4\u547d\u4e4b\u865e\u7684\u4e25\u91cd\u526f\u4f5c\u7528\u3002<\/p>\n\n\n\n

\u79d1\u7f57\u62c9\u591a\u5927\u5b66\u5b89\u8212\u5179\u533b\u5b66\u9662\u6821\u533a(University of Colorado Anschutz Medical Campus)\u836f\u5242\u5b66\u6559\u6388\u5b89\u5fb7\u68ee(Peter Anderson)\uff0c\u67d0\u4e9b\u6f5c\u5728\u526f\u4f5c\u7528\u5e76\u975e\u65e0\u5173\u7d27\u8981\u7684\u5f71\u54cd\u800c\u5df2\uff0c\u6709\u4e00\u4e9b\u836f\u7269\u5176\u5b9e\u5e94\u8be5\u5b8c\u5168\u907f\u5f00\u5408\u5e76\u4f7f\u7528\u3002<\/p>\n\n\n\n

\u5b89\u5fb7\u68ee\u6307\u51fa\uff0c\u907f\u514d\u836f\u7269\u5408\u5e76\u4f7f\u7528\u5728\u67d0\u4e9b\u60c5\u51b5\u4e0b\u975e\u5e38\u65b9\u4fbf\u7ba1\u7406\uff0c\u300c\u4f46\u5728\u5176\u4ed6\u60c5\u51b5\u4e0b\uff0c\u5219\u8981\u7279\u522b\u5c0f\u5fc3\u300d\u3002<\/p>\n\n\n\n

\u56fd\u5bb6\u5e7f\u64ad\u516c\u53f8\u62a5\u5bfc\u6307\u51fa\uff0c\u611f\u67d3\u65b0\u51a0\u75c5\u6bd2\u60a3\u8005\u4e0d\u8bba\u4f7f\u7528\u8f89\u745e\u6297\u75c5\u6bd2\u65b0\u836fPaxlovid\u6216\u9ed8\u514b(Merck)\u6297\u75c5\u6bd2\u65b0\u836f\u300c\u83ab\u7eb3\u76ae\u62c9\u97e6\u300d(molnupiravir)\uff0c\u90fd\u5fc5\u987b\u53d7\u5230\u533b\u5e08\u53ca\u836f\u5242\u5e08\u7684\u4ed4\u7ec6\u76d1\u7763\uff0c\u8fd9\u4e24\u6b3e\u6297\u75c5\u6bd2\u65b0\u836f\u5e76\u4e0d\u662f\u6240\u6709\u67d3\u75ab\u60a3\u8005\u90fd\u80fd\u5b89\u5168\u4f7f\u7528\u3002<\/p>\n\n\n\n

\u4e13\u5bb6\u8b66\u544a\u8bf4\uff0c\u67d0\u4e9b\u666e\u904d\u4f7f\u7528\u7684\u6297\u8840\u8102\u836f\u7269\u3001\u6297\u51dd\u8840\u5242\u4e0e\u6297\u5fe7\u90c1\u5242\u7b49\uff0c\u9047\u5230\u505a\u4e3a\u9e21\u5c3e\u9152\u7597\u6cd5\u7684\u6297\u75c5\u6bd2\u836f\u7269\u65f6\uff0c\u53ef\u80fd\u4ea7\u751f\u4e25\u91cd\u526f\u4f5c\u7528\uff0c\u6050\u6709\u81f4\u547d\u5371\u9669\u3002<\/p>\n\n\n\n

\u7f8e\u56fd\u98df\u836f\u5c40\u6838\u51c612\u4ee5\u4e0a\u5fc3\u810f\u75c5\u3001\u7cd6\u5c3f\u75c5\u60a3\u8005\u4f7f\u7528Paxlovid\uff0c\u6cbb\u7597\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u7684\u65b0\u51a0\u75c5\u6bd2\u611f\u67d3\u75c5\u60c5\uff0c\u964d\u4f4e\u4f4f\u9662\u6216\u6b7b\u4ea1\u98ce\u9669\u3002\u5bf9\u4e8e\u60a3\u6709\u4e25\u91cd\u80be\u810f\u75c5\u6216\u809d\u810f\u75be\u75c5\u7684\u60a3\u8005\uff0c\u98df\u836f\u5c40\u5219\u4e0d\u5efa\u8bae\u4f7f\u7528Paxlovid\u3002<\/p>\n\n\n\n

\u4e3a\u4e86\u907f\u514d\u836f\u7269\u526f\u4f5c\u7528\uff0c\u98df\u836f\u5c40\u9650\u5236\u300c\u83ab\u7eb3\u76ae\u62c9\u97e6\u300d\u53ea\u80fd\u4f9b\u6210\u5e74\u4eba\u4f7f\u7528\uff0c\u4f7f\u7528\u524d\u63d0\u5219\u662f\u83b7\u5f97\u6388\u6743\u7684\u5176\u4ed6\u7597\u6cd5\uff0c\u4f8b\u5982\u5355\u682a\u6297\u4f53(monoclonal antibody)\u836f\u7269\uff0c\u65e0\u6cd5\u53d6\u5f97\u6216\u5bf9\u60a3\u8005\u4e0d\u9002\u5b9c\u3002<\/p>\n\n\n\n

Paxlovid\u9e21\u5c3e\u9152\u7597\u6cd5\u662f\u7531\u4e24\u952d\u6297\u75c5\u6bd2\u836f\u7269nirmatrelvir\u52a0\u4e0a\u4e00\u952d\u6297\u7231\u6ecb\u75c5\u6bd2\u836f\u7269\u300c\u5229\u6258\u90a3\u97e6\u300d(ritonavir)\u7ec4\u6210\u3002\u300c\u5229\u6258\u90a3\u97e6\u300d\u53ef\u4ee5\u6291\u5236\u540d\u79f0\u4e3aCYP3A\u7684\u809d\u810f\u9175\u7d20\uff0c\u8ba9\u8fd9\u9879\u9e21\u5c3e\u9152\u7597\u6cd5\u5f97\u4ee5\u51cf\u7f13\u4eba\u4f53\u5206\u89e3\u6297\u75c5\u6bd2\u836f\u7269\u7684\u8fc7\u7a0b\uff0c\u8ba9\u836f\u6548\u65f6\u95f4\u7ef4\u6301\u66f4\u4e45\u3002<\/p>\n\n\n\n

\u62a5\u5bfc\u6307\u51fa\uff0cPaxlovid\u9e21\u5c3e\u9152\u7597\u6cd5\u82e5\u4e0e\u9488\u5bf9CYP3A\u809d\u810f\u9175\u7d20\u4ea7\u751f\u4f5c\u7528\u7684\u836f\u7269\u4e00\u540c\u4f7f\u7528\uff0c\u4ea4\u53c9\u4f5c\u7528\u4e4b\u4e0b\u836f\u6548\u6050\u5c06\u5347\u9ad8\u4e3a\u5bf9\u4eba\u4f53\u6709\u6bd2\u7684\u5371\u9669\u7a0b\u5ea6\u3002<\/p>\n\n\n\n

\u9047\u5230Paxlovid\u9e21\u5c3e\u9152\u7597\u6cd5\u65f6\u53ef\u80fd\u51fa\u73b0\u5371\u9669\u526f\u4f5c\u7528\u7684\u836f\u54c1\uff0c\u9664\u4e86\u6297\u8840\u8102\u836f\u7269\u3001\u6297\u51dd\u8840\u5242\u4e0e\u6297\u5fe7\u90c1\u5242\u4e4b\u5916\uff0c\u8fd8\u5305\u62ec\u6297\u766b\u75eb\u836f\u7269\u3001\u6cbb\u7597\u5fc3\u5f8b\u4e0d\u6574\u836f\u7269\u3001\u9ad8\u8840\u538b\u836f\u7269\u53ca\u80c6\u56fa\u9187\u836f\u7269\u3001\u6297\u7126\u8651\u836f\u7269\u3001\u514d\u75ab\u6291\u5236\u5242(immunosuppressants)\u3001\u7c7b\u56fa\u9187(steroids)\u836f\u7269\u3001HIV\u75c5\u6bd2\u836f\u7269\u3001\u52c3\u8d77\u529f\u80fd\u969c\u788d(erectile dysfunction, ED)\u836f\u7269\u7b49\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u56fd\u5bb6\u5e7f\u64ad\u516c\u53f8(NBC)\u62a5\u5bfc\uff0c\u8f89\u745e\u836f\u5382(Pfizer)\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u53ca\u836f\u7269\u7ba1\u7406\u5c40(FDA)\u6838\u51c6\u7684\u6297\u65b0\u51a0\u75c5\u6bd2\u53e3\u670d\u7528\u836f […]<\/p>\n","protected":false},"author":1,"featured_media":786006,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12,95],"tags":[],"_links":{"self":[{"href":"https:\/\/test.seehua.com\/index.php?rest_route=\/wp\/v2\/posts\/786005"}],"collection":[{"href":"https:\/\/test.seehua.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/test.seehua.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/test.seehua.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/test.seehua.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=786005"}],"version-history":[{"count":0,"href":"https:\/\/test.seehua.com\/index.php?rest_route=\/wp\/v2\/posts\/786005\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/test.seehua.com\/index.php?rest_route=\/wp\/v2\/media\/786006"}],"wp:attachment":[{"href":"https:\/\/test.seehua.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=786005"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/test.seehua.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=786005"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/test.seehua.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=786005"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}